Members list


AZIZI Michel

CHAZOT Charles

ESCHALIER Romain

FOUQUE Denis

HUTTIN Olivier

LAVILLE Maurice

LE CORVOISIER Philippe

LEGRAND Matthieu

LONDON Gérard

MEBAZAA Alexandre

ROSSIGNOL Patrick

STENGEL Bénédicte

TILMAN Drüeke

WAGNER Sandra

ZANNAD Faiez


 

Michel Azizi is Professor of Vascular Medicine and Head of the Clinical Investigation Center at the Hôpital Européen Georges Pompidou, Paris. He received his MD from René Descartes University and his PhD from Pierre et Marie Curie University, Paris, France.

 

He is a past member of the Clinical Research Commission of the APHP (Assistance Publique des Hôpitaux de Paris). His main research interests include the physiology, genetics and pharmacology of the renin–angiotensin–aldosterone system, and of the haematological peptide, AcSDKP.

 

He has published more than 100 papers in peer reviewed journals, many of which have focused on the renin-angiotensin-system. He has received the Jean Hamburger prize for Medical Research in 2007.

 


 

Charles Chazot studied in Medical School at Lyon 1 University from 1975-1981, then was medical volunteer in Akbou, Algeria from June 1982 to September 1983. He specialized in nephrology in Lyon, France between 1983 and 1989. He joined the Tassin dialysis unit in 1989 run by Dr Guy Laurent and Dr Bernard Charra. He is a private practitioner in Nephrology from 1989 until now with main activities in hemodialysis and clinical nephrology. He was a research fellow in 1994 at Harbor-UCLA Medical Center in the nephrology division of Pr J.D. Kopple, expert in the field of nutritional problems among CKD and dialysis patients. From July 2007 to December 2013 he was Medical Director and General Manager of the Tassin dialysis unit that belongs to Fresenius Medical Care since 1998. In 2009 he obtained a Master Degree in Management of Healthcare Units. Since January 2014 he is NephroCare Country Medical Director for France.

 

Dr Chazot has a special interest in the fields of nutrition, extra-cellular volume and blood pressure controls in dialysis patients. He has published 115 peer reviewed papers, written 3 book chapters and is a regular reviewer for nephrology journals.

 


 

Pr. Romain Eschalier was educated in Nancy and Clermont-Ferrand. He works at the Department of Cardiology and Cardiovascular Diseases at the University of Clermont-Ferrand where he is currently principal investigator of 5 clinical studies.

 

He is a member of the publishing company "Stimuprat" but also of various learned societies since 2009. He is very involved in the creation and operation of Cardiauvergne network for the coordination of care for ambulatory management of patients with heart failure in Auvergne. He has published 36 publications and made 40 communications in national and international conferences.

 


 

Denis Fouque, MD, PhD, is Professor of Nephrology at the University Claude Bernard Lyon1, and Associate Chief of the Division of Nephrology at the Centre Hospitalier Lyon Sud in Lyon, France. He is the current Research Vice President (Health Affairs) at the Université Claude Bernard Lyon, the largest medical school in France (2012-2016).

 

Dr Fouque has published 250 papers, including reviews, meta-analyses and 18 book chapters, among which 2 chapters in The Kidney, Brenner and Rector, 2012 and 2015. His current h factor is 48. His research fields are in nutrition and metabolism in chronic kidney disease and dialysis. He is director of the adipocyte dysfunction research group in INSERM 1060 at the University Claude Bernard Lyon1. Dr Fouque also got training in Evidence based Medicine by founding the Cochrane Collaboration Renal Group in 1997 and being the Co-ordinating Editor until 2001. Dr Fouque was President of the International Society for Renal Nutrition and Metabolism (2004–2006), Editor-in-Chief of the Journal of Renal Nutrition (2003-2011) and chairman of the ERA-EDTA Nutrition Guideline (2007).

 

Dr Fouque is currently vice-chairman of the European Renal Best Practice group of ERA-EDTA and a member of the K-DIGO Advisory Board. He has been an ERA-EDTA Council member from 2012 to 2015, and chairman of the abstract selection committee from 2013 to 2016.

 


 

Olivier Huttin works in the cardiology department of the University Hospital of Nancy. His work focuses on imaging techniques applied to heart failure, valvular heart disease and cardiomyopathy. A graduate of medicine with validation of degrees on echocardiography and noninvasive cardiac imaging and a fellowship at London's University Hospital (The Heart Hospital), he practices clinical activity and cardiovascular imaging research with transthoracic echocardiography achieving and stress as well as magnetic resonance imaging.

 

He works closely with the clinical investigation centers on different areas including the assessment of cardiovascular remodeling, heart failure and diastolic dysfunction. His involvement in multimodality cardiac imaging also gives him an expertise in the field of tissue characterization and evaluation of right ventricular function.

 

He is currently validing a diploma focused on screening of cardiovascular aging and impact of new biomarkers and imaging, including the role of myocardial deformation.

 


 

Maurice Laville is head of the Department of Nephrology at Lyon Sud University Hospital and Professor of Therapeutics at the Claude Bernard University in Lyon, France. As a head of the nephrology division, he has developed a comprehensive approach to the care of renal patients. His main focus of interest is chronic kidney disease, and in this context he participated as coordinator is principal investigator in numerous clinical trials, from industrial promotion or as part of PHRC, as Alchemist study. He is a member of the team INSERM U1060 CarMeN at the University Claude Bernard Lyon 1, the research network INI-CRCT, and the steering committee of the REIN-CKD cohort.

 

In continuation of its clinical, Maurice Laville has created and led for nearly 15 years a health network (TIRCEL) dedicated to early care and coordination of care in chronic kidney disease. This network has supported nearly 1,600 patients in the Rhône-Alpes region.

 

He is also president of the Association for the Use of Artificial Kidney Lyon (AURAL), which cares for nearly 800 patients in the Rhône-Alpes region. Maurice Laville was president of the Society of Nephrology 2011 to 2013, it has since May 2015 Chairman of the Kidney Foundation.

 


 

Dr. Philippe Le Corvoisier completed his medical studies in Paris and obtained a doctorate in medicine in 2000, followed by a DES in cardiovascular pathology in 2001 and a cellular and molecular biology pHD in 2006. In 2013, he obtained the HDR at the University of Paris XII (Créteil). Currently, Dr. Corvoisier is PU-PH in therapeutic, and coordinator of the Clinical Investigation Centre 1430 of Henri Mondor Hospital in Créteil.

 

On another side, he held academic positions as head of teaching and education DFASM3 of therapeuthic, head of the EU clinical research M2 tissue therapies, cell and gene and then co-head of DU technician of clinical research and biological resources.

 

It also participates in committees and working groups, as an elected member of the Committee on Research of the University of Paris-Est Creteil and member of the education committee of the Créteil Medical School.

 

His main areas of research interest are cardioprotection strategy in acute myocardial infarctus and evaluation of innovative therapies in conventional cardiology.

 


 

Dr Matthieu Legrand is associated Professor in Anesthesiology and Critical care medicine and holds a PhD in physiology. He Works in the Department of anesthesiology, Critical care and burn unit of St-Louis hospital, (university Paris Diderot) , in Paris, France.

 

He has carried preclinical and clinical research in the field of critical care medicine with a special interest in the pathophysiology and treatment of acute kidney injury and in burn critical care. He has served as a reviewer for several peer-review journals and expert in the field of critical care for several commitees and task forces.

 


 

Gérard M. London (born 03/04/1943 in Paris) graduate from medical school of Charles University in Prague in July 1966. He specialized in Nephrology (1967-1971) at Paris Medical School and became the chief of the department of Nephrology-Hemodialysis of the Manhes Hospital from 1970-2009. From 1991 to 1998 he was member of the Council of French Society of Nephrology and from 1994 to 1999 of the Council of French Society of Hypertension. Member of the Council of European Renal Association (ERA-EDTA) from 2002 to 2006, he is presently member of the Scientific Council of International Society of Hypertension. President of ERA-EDTA (European Renal Association – European Dialysis and Transplant Association) from for 2008-2011, he is presently the Chair of EURECA-m working group.

 

Member of International/American/French Societies of Hypertension, and Honorary Member of the Czech Society of Hypertension, Dr London is Member of International/European/American/ French Societies of Nephrology, and Honorary Member of Czech/Italian/Slovak/Spanish/Polish Societies of Nephrology, and European Society of Cardiology.

 

Dr. London was awarded the Gold Medal of Charles University in Prague, and Paul Milliez Award of European Soc. of Hypertension. Dr.London is presently member of the Editorial Board of Journal of Nephrology, Journal of Hypertension, Nephrol. Dial. Transplant., Blood Purification, and serves as reviewer for Circulation, Hypertension, Circulation Research, Kidney International, Journal of American Society of Nephrology, and several others. He published in this field more than 350 publications in peer review journals and several chapters in the books. Present Hirsch index 69.

 


 

Alexandre Mebazaa , MD, PhD, FESC, is Professor of Anaesthesiology and Critical Care Medicine at the Hôpital Lariboisière, University Paris 7, France. H,is research interests include mechanisms of contractile impairment during acute heart failure and global studies on biomarkers in acute heart failure. He acted as member or Chair of several Steering Committees including SURVIVE, COMPOSE, TRUE-HF. He is also involved in several European and global registries on circulatory failure. He has authored or co-authored more than 200 papers and is Lead-Editor of the Acute Heart Failure textbook. Dr. Mebazaa also serves as the Chair of Department of Anesthesiology and Critical Care in Paris.

 


 

Patrick Rossignol (Nancy, FRA) Patrick Rossignol, MD, PhD, is professor of Therapeutics, Nephrologist and Vascular medicine specialist, Deputy Director of Nancy Plurithematic Clinical Investigation center (CIC)-Inserm wich he leads with the Pr Faiez Zannad.

 

He has participated/is participating in several EU FP6-7 programs (Ingenious Hypercare: Coord A; Zanchetti; MEDIA: Coord: W. Paulus; HOMAGE & FIBROTARGETS : Coord F. Zannad , Nancy CIC). He is the PI of the ongoing largest double blind (spironolactone vs. placebo) academic cardiovascular outcome randomized controlled trial in hemodialysis (ALCHEMIST)and steering committee member of several international randomized clinical trials.

 

He is coordinating a French network of excellence endorsed by F-CRIN (French Clinical research Infrastructure Network, the French affiliate of ECRIN/ERIC: Cardiovascular and Renal Clinical Trialists (INI-CRCT www.inicrct.org) since 2014. He is also coordinating the University Hospital “French Government Investment for the Future” Fighting Heart Failure program (2016-2020).

 

He is a EURECA-m (cardiorenal working group of ERA-EDTA: The European Nephrology Dialysis Transplantation Association) member since its creation in 2009 and got elected as board member for 6 years in 2013.

 


 

Dr. Bénédicte Stengel completed his medical studies at the Necker Hospital in Paris and received a PhD in Epidemiology and Public Health at the University Paris Sud. In 2000, she performed a sabbatical year at Johns Hopkins University in Baltimore in the USA. Currently, Bénédicte Stengel is Director of Research at INSERM, the National Institute of Health and Medical Research, where she heads a research group on the Epidemiology of Chronic Renal Disease, within the Research Center Epidemiology and Population Health in Villejuif.

 

She contributed to the establishment of the register REIN (Epidemiology and Information Network in nephrology) in France, and coordinates the CKD cohort (Chronic Kidney Disease) REIN winner of the call for Cohorts Investments for the Future project launched in 2010. She is a member of the steering committee Chronic Kidney Disease Prognosis Consortium and participates in several international research consortia on chronic kidney disease.

 

Bénédicte Stengel research work focused on descriptive epidemiology and trends in ESRD, determinants and biomarkers of progression and complications of chronic kidney disease, as well as assessing its prognosis long-term.

 


 

Tilman Bernhard Drüeke, MD, FRCP, is INSERM emeritus research director and member of Unit 1018 of Villejuif. He received his MD from Tübiengen University, Germany in 1968. From 1969 to 2009, he had medical and scientific activities as assistant, and as associated professor in the Nephrology department and as director of Unit 90 of INSERM, in the Necker hospital in Paris.

 

His main research interests are chronic kidney disease and its complications (disturbances of bone and mineral metabolism, anemia, hypertension and cardiovascular involvement) and its treatment with hemodialysis. He is or was a member of several societies, scientific committees and advisory councils, co- chairman of the working group on KDIGO CKD - MBD and member of the working group on KDIGO anemia.

 

He is Editor Emeritus of NDT and was associate editor of CJASN and is now associate editor of Kidney International. He has published over 500 original articles and his h-index is currently 65.

 


 

With a pHD of Burgundy University, Sandra Wagner is specialized in nutrition sciences and epidemiology. She was a post-doctoral fellow in the Epidemiology and Population Health Research Center. She is currently biostatistician and epidemiologist for INI-CRCT network.

 


 

Faiez Zannad, MD, PhD is Professor of Therapeutics at Université de Lorraine, Nancy, France. He obtained his MD, with a PhD in human biology, and a PhD in clinical pharmacology at Université de Lyon and Oxford). He is currently Director of the INSERM Clinical Investigation Center, director of the Inserm Cardiovascular CIC network and head of the Division of Heart Failure and Hypertension at “Institut Lorrain du Coeur et des Vaisseaux” in the Centre Hospitalier et Universitaire of Nancy.

 

His major contributions are: The implementation of Heart Failure Care disease management in Lorraine. Authoring major advances in the field of mineralocorticoid, he made significant contributions to evidence based heart failure therapy leading to changes in treatment practices (IA Recommendations) and to increased survival in heart failure.

 

His research fields are:  heart failure, Aldosterone, Fibrosis, Biomarkers, clinical trials and hypertension. He coordinates several EU FP7  Heart failure Omics and AGEing (HOMAGE), FIBRosis as a TARGET in Heart Failure (FIBROTAGERTS), and an France-Germany ANR. FOCUS-MR. He is WP leader in the EU FP7 The MEtabolic Road to DIAstolic Heart Failure (MEDIA), and of the FHU CARTAGE and of the RHU FIGHT-HF, Nancy.

 

He is also the coordinator of the Contract de Plan Etat Region in Lorraine (CPER) "Technological Innovations, Modeling and Personalized Medicine". He holds several patents in the field of biomarkers. Co-founder of the telemedicine start –up “Cardiorenal Sarl”. Convenor and organizer of the CVCT «Global CardioVascular Clinical Trialists Forum» (www.globalcvctforum.com) with Inserm, US-NHLBI, EMA and FDA, since 2003, now at Washington DC. He has served as chairman of the French Society of Hypertension (2007 – 2008), and President of the Working Group Pharmacology and Drug Therapy of European Society of Cardiology (2008-2010).

 

He participates in many scientific editorial committees. Author of 573 publications (30/10/2016), totaling 81218 citations, h-Index = 85.

 


 

 

 

CRCT Cardiovascular & Renal Clinical Trialists

 

CIC-P - INSTITUT LORRAIN DU COEUR ET DES VAISSEAUX LOUIS MATHIEU

4, rue du Morvan 54500 VANDOEUVRE-LES-NANCY - FRANCE

 

Contact : inicrct@chru-nancy.fr  - +33 3 83 15 74 39